Abstract – Dr. Rajesh Sunasee

Dr. Rajesh Sunasee, Department of Chemistry, Brandon University

Engineering Nanoparticles for targeted protein, drug and gene delivery.

Abstract

In the past few decades, nanotechnology for drug delivery has attracted a great deal of attention. Usually, once a drug is synthesized, the next challenge is its delivery to the targeted infected site. Targeted drug delivery has become an integral part in the process of drug development as it can significantly increase the therapeutic efficacy of drugs. This seminar will discuss the use of the emerging polymeric micelles (so-called nanogels) for the encapsulation of proteins, drugs and genes as well as their controlled release. The synthesis and characterization of these drug delivery carriers will be discussed. Normally, the ideal choices for an efficient drug delivery vehicle are that it should be biodegradable, non-toxic, able to overcome the physiological barriers in the body, and able to withstand the immune system long enough to perform its job.